Leiomyosarcoma is a malignant tumor that grows from the muscles. The disease is relatively rare; mass can occur on any body part. Treatment consists of surgery combined with chemotherapy or radiation therapy.
Leiomyosarcoma is an aggressive tumor with a high recurrence rate and early metastases. The disease usually develops around the age of 60. Often, leiomyosarcoma develops in the uterus, stomach, bladder, and small intestine.
In most cases, tumors at an early stage are asymptomatic. However, as the mass grows, it causes pain and swelling, fatigue, and weight loss. Leiomyosarcoma causes typical symptoms, depending on where it appears. For example, abnormal bleeding if the tumor is in the uterus, bloody vomiting if it is in the alimentary tract, and others.
Imaging tests (X-ray, CT, MRI, PET) give a detailed tumor image and determine its size and localization. The doctor then takes a sample of the mass and examines it under a microscope (biopsy) to determine the type and stage.
The treatment of choice for leiomyosarcoma is the surgical removal of the tumor. Depending on the tumor size and location, surgeons operate either laparoscopically (minimally invasive) or with a da Vinci robotic system. In addition, chemotherapy and radiation therapy are often used to treat tumors that have returned or metastasized to other body parts.
Often, postoperative radiation helps kill any remaining cancer cells around the tumor site. Radiation damages cancer cells, preventing them from multiplying and spreading. In some cases, neoadjuvant radiation therapy irradiates the tumor before an operation, reducing mass. Oncologists use brachytherapy, external beam radiation therapy, or stereotactic radiation therapy.
Where can I get Leiomyosarcoma treatment?
What are the best clinics for Leiomyosarcoma treatment?
Who are the best doctors for Leiomyosarcoma?
Prof. Dr. med. Roland Ladurner from Academic Hospital Martha-Maria Munich
Prof. Dr. med Harald-Robert Bruch, MSc, PhD from Oncological and Haematological Praxis Clinic Bonn
Prof. Dr. med. Rudiger von Eisenhart-Rothe from University Hospital rechts der Isar Munich
Prof. Dr. med. Florian Bassermann from University Hospital rechts der Isar Munich
Prof. Dr. med. Helmut Friess from University Hospital rechts der Isar Munich