Nephroblastoma is a malignant tumor of the kidney. The disease usually does not cause symptoms until it grows. However, the condition has a good prognosis and responds well to treatment. There are various therapy options, from surgery and radiation to targeted methods such as ablations and immunotherapy.
Nephroblastoma (also called Wilms's tumor) is a cancerous formation that develops in the kidney. According to statistics, the tumor occurs mainly in children and is extremely rare in adults. Data show that about 6-10% of all childhood malignancies are nephroblastomas. Approximately 1 in 100,000 kids, usually 1-4 years old, suffer from this disease yearly.
In the initial stages, patients have no complaints. However, when nephroblastoma grows, it is characterized by an abdomen protrusion, fatigue, fever, rarely - abdominal pain, blood in the urine, and high blood pressure.
To identify Wilms's tumor, doctors do an abdomen ultrasound, a CT scan, or an MRI with contrast to reveal the size of the tumor and metastases. In addition, oncologists use a biopsy (examination of a piece of the tumor under a microscope).
As a rule, physicians manage to get rid of the tumor through surgery. Besides, oncologists might recommend immunotherapy and radiation treatment, depending on the size of the nephroblastoma. If the lump is too large for surgery, physicians first give chemotherapy to shrink it.
Alternative treatment for nephroblastoma is locally advanced chemotherapy and ablation procedures for metastasis. In addition, oncologists can advise proton beams instead of traditional radiation in some scenarios.
Where can I get Nephroblastoma treatment?
What are the best clinics for Nephroblastoma treatment?
Who are the best doctors for Nephroblastoma?
Prof. Dr. med. Jurgen Gschwend from University Hospital rechts der Isar Munich
Prof. Dr. med. Florian Bassermann from University Hospital rechts der Isar Munich
Prof. Dr. med. Christian Brandts from University Hospital Frankfurt am Main of Goethe-University
Prof. Dr. med. Felix K. H. Chun, MA, FEBU from University Hospital Frankfurt am Main of Goethe-University
Prof. Dr. med. Hubert Serve from University Hospital Frankfurt am Main of Goethe-University