Assoc. Prof. Dr. Mehmet Salih İyikesici

Assoc. Prof. Dr. Mehmet Salih İyikesici is a Turkish medical oncologist based in Istanbul, with extensive clinical and academic experience in diagnosing and systemically treating solid tumors. Having completed both his internal medicine training and medical oncology fellowship at Istanbul University, he has dedicated his career to managing complex, advanced-stage cancers. He approaches medical oncology with a particular interest in the relationship between tumor biology, cellular metabolism, and the body's response to cancer treatment. His clinical work encompasses several major solid tumors, including breast, pancreatic, gastric, colorectal, and lung cancers, as well as prostate and other urological malignancies. Rather than viewing treatment as a sequence of isolated procedures, he emphasizes developing an individual strategy that considers the cancer type, disease stage, previous treatments, and the patient's overall condition. An important part of his approach is integrating conventional oncology with metabolic and supportive treatment concepts. His clinical model includes metabolically supported chemotherapy, local and whole-body hyperthermia, hyperbaric oxygen therapy, and individualized nutritional planning, including ketogenic-style diets. He also has a particular interest in immunotherapy and approaches intended to address the metabolic changes associated with tumor growth. These complementary methods are considered alongside established oncological treatments, rather than as a replacement for appropriate standard cancer care. The medical philosophy places considerable attention on the patient's condition beyond the tumor itself. Treatment planning also considers nutritional status, treatment tolerance, metabolic health and the management of therapy-related difficulties. He works within an integrative oncology framework that brings together medical oncology, radiology, nuclear medicine, and radiation oncology. The intention is to coordinate different aspects of cancer care within one treatment plan, adapted to the individual clinical situation.