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Cytoreductive Surgery + Hyperthermic Intraperitoneal Chemotherapy (HIPEC) | Teknon Peritoneal Cancer Institute, Spain

Cytoreductive Surgery + Hyperthermic Intraperitoneal Chemotherapy (HIPEC) | Teknon Peritoneal Cancer Institute, Spain

Barcelona, Spain

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About the offer

Cytoreductive surgery is a type of surgery that removes as much cancerous tissue as possible. It is often done when cancer has grown into tumors or masses in the abdomen. After cytoreductive surgery, hyperthermic intraperitoneal chemotherapy (HIPEC) treatment involves giving high chemo doses directly to the peritoneal cavity. The name "hyperthermic" means that the chemotherapy is heated to a high temperature to make it work better at killing cancer cells. During the procedure, the patient is put to sleep, and a small cut is made in the abdomen. The surgeon takes out as much of the cancerous tissue as possible. The chemo drugs are heated to the right temperature and given to the peritoneal cavity.  The chemotherapy is moved to the peritoneal cavity (usually around 90 minutes) for a certain amount of time. After that, the chemotherapy is drained out of the peritoneal cavity, and the cut is closed. This surgical method was developed by Dr. Paul Sugarbaker (USA) to remove all the peritoneal tumor deposits. The extent of surgery will depend on the number and distribution of the tumor deposits that the surgeons encounter. Due to the complexity of this surgery, it should only be performed by surgeons who are highly specialized and experienced in this procedure. Once the tumor deposits are surgically removed, the surgical team administers HIPEC ( heated intraperitoneal chemotherapy). During this part of the procedure, the abdomen is filled with heated chemotherapy solution and circulated with the help of a specialized device for 60-90 minutes, which is used to treat the microscopic residuals of the tumor and achieve a better result. Cytoreductive surgery and HIPEC removes a lot of cancerous tissue, which may not be possible with other types of treatment. High doses of chemo given directly to the tumor can kill cancer cells better than chemotherapy is shown all over the body. Patients may also live longer and have better quality of life. Types of cancers that can lead to peritoneal carcinomatosis and could benefit from Cytoreductive Surgery and HIPEC:Pseudomyxoma Peritonei (PMP)Appendix cancerOvarian cancerColorectal cancerMesotheliomaStomach cancerMany other types of cancer can cause carcinomatosis, such as endometrial cancer, small bowel cancer, hepatobiliary and pancreatic cancers, neuroendocrine tumors, and others.

What’s included

Medical service

  • clinical history-taking
  • medical records review
  • physical examination
  • consultation with an abdominal surgeon
  • consultation with an anesthesiologist
  • consultation with an oncologist
  • consultation with a dietitian and nutrition expert
Laboratory tests
  • complete blood count (CBC)
  • blood type test (ABO, Rh)
  • biochemical analysis of blood (kidney and liver function tests, thyroid function tests, electrolytes, glucose, lipid panel)
  • inflammation blood tests
  • coagulation studies
  • urinalysis
  • ultrasound imaging of the abdomen
  • CT/MRI scan of the abdomen
  • histopathological specimen examination
  • electrocardiogram (ECG)
  • chest X-ray
  • preoperative patient preparation
  • cytoreductive surgery
  • hyperthermic intraperitoneal chemotherapy (HIPEC)
  • cost for any reoperation or complication management during hospitalization
  • postoperative care
  • symptomatic treatment
  • cost of essential medicines
  • cost of essential materials
  • general anesthesia
  • hospitalization
  • stay in ICU
  • blood bank material
  • nursing service
  • discharge medical records
  • further recommendations
Distant service
  • follow-up consultations for the post-treatment period

Extra add-ons

Airport transfer
Single room
Companion hospitalization
Hospital meals
Personal coordinator


AiroMedical support
Payment protection
Patient advocacy
Price match

Meet the provider

Dr. Domenico Sabia

general surgery, peritoneal oncology, HIPEC and PIPAC surgery


Why to choose us?

Specialized Peritoneal Cancer Institute
The Peritoneal Cancer Institute operates at the clinical base of the Teknon Medical Centre, one of the largest multidisciplinary hospitals in Spain, which allows the patient to receive any necessary medical care and provide the care and supervision needed in the postoperative period. The hospital regularly undergoes international certification and has been certified by Joint Commission International seven times, guaranteeing high quality and safety for medical services.
Experience in numbers
We are a high-volume dedicated center performing 3 Cytoreductive Surgeries with HIPEC procedures weekly. More than 170 patients per year receive advanced comprehensive cancer treatment, including cytoreductive surgery, HIPEC, PIPAC (pressurized intraperitoneal aerosolized chemotherapy), and systemic oncologic therapy.
Operation guaranty
Thanks to our massive experience, our team has developed a package covering all possible complication management procedures, including possible reoperation after HIPEC surgery. We know that many cases can be complicated due to the nature of the disease, and we ensure that patients can have adequate surgical management without additional fees.


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Carrer de Vilana, 12, 08022 Barcelona Spain


How effective is Cytoreductive Surgery with HIPEC?

Cytoreductive Surgery with HIPEC can cure patients, especially those with appendix cancer, PMP, some forms of mesothelioma, and ovarian cancer, even when there is a large amount of tumor in the abdomen at the time of diagnosis. For other tumors, such as colon cancer and gastric cancer, the CRS HIPEC treatment is applied when there is a more limited amount of tumor in the abdomen to achieve the best results. For all tumors that develop peritoneal metastasis, a chance for cure is only possible if surgery ( CRS HIPEC) can be included as part of the treatment.

Can HIPEC replace systemic chemotherapy?

In most cases, both HIPEC and systemic chemotherapy are required to achieve the best results. The methods are complementary and do not replace each other. Some kinds of tumors, such as PMP, do not benefit from systemic chemotherapy, and therefore, CRS and HIPEC are the only treatments patients receive.

What factors determine the indication for surgery and prognosis?

Many factors need to be evaluated before the decision to recommend CRS and HIPEC is made and also to determine the prognosis once surgery is done. The type of primary tumor ( such as appendix, colon, ovary, mesothelioma, etc. ) and the amount of the peritoneal metastasis that are present are some of the most important factors. The peritoneal carcinomatosis index (PCI) describes the number of tumors presents in the abdomen. Computed tomography (CT), MRI, and or diagnostic laparoscopy can be used to estimate the PCI before surgery, but the final assessment is done during surgery. The intraoperative PCI, as well as the CC score ( a description of the completeness of the surgical removal of the tumor), are essential to determine the prognosis after surgery.

What are the risks associated with the procedure?

Like any major surgery, CRS has specific risks, such as bleeding, infection, and the need for reoperation. Specialized centers can maintain a relatively low risk of serious complications, less than 10-15%. The mortality risk after surgery in specialized centers is also low, less than 2%. Minor complications and side effects are more common and generally happen in about a third of the patients.

How long does the procedure take?

Cytoreductive surgery with HIPEC is a complex surgical intervention that can take as many as 14 hours or more, depending on the extent of the operation and the general condition of the patient. The average duration, including the HIPEC, is approximately 7 hours.

How long do I need to stay in the hospital after the procedure?

The total period of hospitalization can typically range from 1 to 3 weeks and will depend on the extent of the surgery needed in each case. For the first 1-2 days, the patient is monitored in the intensive care unit and then transferred to an individual room on the ward. Patients are encouraged to be out of bed and ambulate during the postoperative period and often receive nutritional support until they can recover their dietary intake.

Do I need to follow a diet before and after treatment?

Yes, a high-calorie, high-protein diet is recommended in preparation for surgery to prepare the body for the post-op period and faster recovery. Depending on the extent and condition of the operation, an individual diet will be compiled for the patient in the postoperative period.

Do I need to stop taking drugs or other medicines before surgery?

Yes, it is recommended that chemotherapy be stopped 2-6 weeks before CRS HIPEC surgery. Your surgeons will determine the exact duration and coordinate with your oncologist. It may also be necessary to stop other drugs before surgery, such as anticoagulants.

How is the follow-up management and control of the disease carried out?

Usually, follow-up diagnostics are carried out every 3-6 months: computed tomography (CT), laboratory tests, and physical exams. The follow-up schedule is coordinated with the patient’s referring physicians. You should consult your doctor if your condition changes between the scheduled follow-up appointments.

What is the cost?

The total price for Cytoreductive Surgery + Hyperthermic Intraperitoneal Chemotherapy (HIPEC) | Teknon Peritoneal Cancer Institute, Spain is €120,000. However, it can vary from the specifics of each case. Get in touch to get an individual estimate.

What is the rating of the offer?

Cytoreductive Surgery + Hyperthermic Intraperitoneal Chemotherapy (HIPEC) | Teknon Peritoneal Cancer Institute, Spain is rated as 9.90 by AiroMedical.

Who is offering a deal?

The provider is Dr. Domenico Sabia.

How long does the offer take?

The offer is designed for 14 days.

Does the offer require you to stay in the clinic overnight?

What are the age restrictions?

The offer is eligible only for adults.

Can I customize the content of the offer?

Yes, the components of the deal can be changed. Get in touch with a vendor to create a personalized proposal.

Does the offer include extra services?

Individual cost estimate. Non-binding 100% free assessment.


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