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Prof. Dr. med. Wolfgang Weber image

Department of nuclear medicine, molecular and radionuclide therapy

Prof. Dr. med. Wolfgang Weber
nuclear medicine, molecular and radionuclide therapy

About the department

The department of nuclear medicine, molecular and radionuclide therapy at University Hospital rechts der Isar of the Technical University (TUM) Munich is one of the largest nuclear medicine centres in Europe, with over 5,500 outpatient thyroid examinations, more than 5,000 PET examinations, over 2,000 examinations in conventional nuclear medicine, and more than 800 inpatients. After the professor, the medical team consists of five senior physicians and eleven assistant physicians. The department is equipped with modern imaging equipment. For example, the world's first combined PET/MRT device was installed as part of a large-scale device initiative by the German Research Society (DFG). Other instruments include a PET/CT of the latest generation, a SPECT/CT (Single-photon emission computed tomography), another SPECT, and a so-called "rapid heart camera". The department is a part of the Roman-Herzog Comprehensive Cancer Center, and an ENETS (European Neuroendocrine Tumor Society) certified centre of excellence for diagnosing and treating neuroendocrine tumours. Scientific research groups study molecular imaging and the diagnosis and treatment of cardiological, oncological, and brain disorders. 

Mainly, the department specializes in treating and diagnosing thyroid diseases, heart disorders, and tumours in different locations. In addition, there are numerous devices for visualization and multiple types of radionuclide therapy in use.

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Treatment and diagnostic focus of the department

Diagnosis:

  • Ultrasound examinations (visualization)
  • Scintigraphy (visualization using mild radiation)
  • Blood tests 
  • Fine-needle punctures (using needles to cut off tissues for testing)
  • Positron emission tomography, PET (visualization)
  • Ga-68 PSMA-PET (for the diagnosis of prostate cancer)
  • Ga-68 DOTANOC PET (for the diagnosis of neuroendocrine tumours)
  • "rapid heart camera" / myocardial perfusion scintigraphy for coronary heart disease diagnosis
  • FDG PET (testing the strength of the heart muscle, Alzheimer's dementia, epilepsy, Parkinson's syndrome diagnosis)
  • Magnetic resonance imaging, MRI
  • Combined PET/MRI 
  • FET-PET (brain tumours diagnosis)

Diseases treated at the department:

  • Thyroid diseases (hypothyroidism, hyperthyroidism)
  • Bronchial carcinoma (lung cancer) 
  • Tumours of the lymphatic tissue (lymphoma)
  • Melanoma (skin cancer)
  • Tumours of the mammary glands (mammary carcinoma)
  • Prostate cancer 
  • Neuroendocrine tumours

Treatment options:

  • Radioiodine therapy
  • Radium-223 (Xofigo®) therapy (to treat prostate cancer with bone metastases)
  • Lu-177 PSMA therapy (to treat resistant prostate cancer with bone metastases)
  • Peptide radioreceptor therapy (PRRT) with 177-lutetium DOTATATE (for the treatment of neuroendocrine tumours)
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Doctor profile

Education

  • Medical School, the University Hospital rehts der Isar of the Technical University of Munich
  • 1995 Medical license to practice
  • 1996-2001 Specialization in nuclear medicine at the Technical University of Munich

Experience

  • 2001-2003 the Faculty of the Department of nuclear medicine at the Technical University of Munich
  • 2003-2007 Associate professor at the University of California, Los Angeles
  • 2007  Chair of the Department of nuclear medicine at the University of Freiburg
  • 2013-2017 Chief of the molecular imaging and therapy service at Memorial Sloan Kettering Cancer Center and Professor of Radiology at Weill-Cornell Medical College, New York
  • 2018 Director of the Department of nuclear medicine, molecular and radionuclide therapy at University Hospital rehts der Isar Munich

Awards, memberships, publications

  • Member of the editorial board at Journal of Nuclear Medicine 
  • Member of the editorial board at European Journal of Nuclear Medicine and Molecular Imaging
  • Member of the editorial board at Clinical Cancer Research 
  • Member of the editorial board at Journal of Clinical Oncology 
  • Author of more than 450 publications
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