Photodynamic Therapy (PDT) at Centre of Advanced Medicine, Frankfurt, Germany

9.30

Frankfurt am Main, Germany

Overview

Age group

Kids, Adults

Type of care

Outpatient

Method

Minimally invasive

About the offer

Photodynamic Therapy (PDT) is an innovative treatment method that uses light to treat a variety of cancers and other diseases. This non-invasive and highly targeted therapy relies on the use of photosensitizers—special substances that make tumor cells sensitive to light. When these photosensitizers are exposed to specific wavelengths of light, typically in the blue to red range, they activate a series of chemical reactions that lead to the destruction of the cancerous tissue. One of the key advantages of PDT is its ability to minimize damage to surrounding healthy cells, making it an ideal treatment for tumors in sensitive or difficult-to-reach locations. The process begins with the administration of a photosensitizer, which is introduced into the patient's body through an intravenous injection, topical application, or oral intake, depending on the location and type of cancer. Once inside the body, the photosensitizer is selectively absorbed by cancer cells, where it accumulates. Upon exposure to light of a specific wavelength—delivered through lasers or light-emitting diodes (LEDs)—the photosensitizer becomes activated. This activation causes the photosensitizer to transfer energy to nearby oxygen molecules, turning them into highly reactive singlet oxygen. Singlet oxygen is a powerful oxidative agent that destroys the tumor cells, leading to their necrosis and, in some cases, apoptosis, which is programmed cell death initiated by the body itself. The localized action of singlet oxygen ensures that only the cancer cells are targeted, and surrounding healthy tissues remain unharmed. This precise targeting of malignant cells is one of the primary reasons PDT is highly effective with minimal side effects compared to more traditional cancer treatments like chemotherapy or radiation. PDT has been shown to be effective for treating a wide range of cancers, including bladder, prostate, basal cell carcinoma, and certain types of lung and esophageal cancer. It is also employed for treating precancerous conditions like actinic keratosis and Bowen’s disease, providing patients with a non-invasive alternative to surgery. PDT is especially valuable in cases where traditional treatment options may be difficult or risky, such as in patients with tumors near critical structures or those with a weakened immune system. Additionally, PDT has applications beyond cancer treatment. It is increasingly being used to manage chronic conditions such as prostatitis, benign prostatic hyperplasia (BPH), and even certain infections, including those caused by bacteria, fungi, and viruses. For these conditions, PDT works by using its light-activated properties to promote healing and immune response while limiting adverse effects. One of the key benefits of PDT is its ability to be used in combination with other treatment modalities. It can be integrated with low-dose chemotherapy, radiation therapy, or even surgical procedures to enhance their effectiveness. PDT's non-invasive nature allows it to be repeated as needed without causing the same degree of trauma or side effects that are common with traditional therapies. This makes it a versatile option for long-term treatment plans, especially for patients who require ongoing management of their condition. While PDT is generally considered safe with few side effects, patients do need to follow certain precautions before and after treatment. Since the photosensitizer makes the skin and eyes more sensitive to light, patients must avoid direct sunlight for a period following the treatment. The treatment itself is typically painless, although some patients may experience temporary redness, swelling, or discomfort in the treated area. The healing process after PDT is usually smooth, with the destroyed tumor cells being replaced by healthy tissue over time. The effectiveness of PDT is further supported by clinical studies and extensive research. In particular, PDT has been shown to significantly improve survival rates in patients with certain types of cancer. One study published in Lancet Oncology demonstrated the superior outcomes of patients with aggressive soft tissue sarcomas when treated with PDT in addition to chemotherapy, compared to those receiving chemotherapy alone. The ability of PDT to enhance the body's immune response, combined with its precise targeting and minimal invasiveness, positions it as a powerful tool in the modern cancer treatment arsenal. In summary, Photodynamic Therapy represents a breakthrough in both cancer and alternative medical treatments. It offers a highly targeted, effective approach to destroying cancer cells while minimizing harm to healthy tissue. With applications across a wide range of cancers and other medical conditions, PDT is rapidly becoming a standard in integrative and holistic treatments, providing patients with a promising alternative or complement to traditional therapies.

What’s included

Medical service

Examination

A comprehensive review of your medical history, current health status, and treatment needs.
Discussion of potential treatment outcomes, risks, and side effects with your medical team.
Tailored PDT treatment plan based on your specific diagnosis (e.g., cancer, precancerous lesions, chronic conditions).
Selection of the appropriate photosensitizer and light wavelength, customized for your condition and tumor type.
In-depth explanation of how PDT works and what to expect during the treatment process.

Diagnosis

Diagnostic tests and imaging (if necessary) to determine the extent and location of the condition or tumor

Treatment

The selected photosensitizer is administered through intravenous infusion, oral intake, or topical application, depending on the targeted area.
Detailed explanation of how the photosensitizer is absorbed and accumulates in the affected cells, making them sensitive to light.
Careful monitoring of the photosensitizer’s distribution within the body.
Targeted application of light, using either a laser or light-emitting diode (LED), to activate the photosensitizer and begin the destruction of cancerous or abnormal tissue.
Specific wavelength light is precisely guided to the treatment area to ensure only the affected cells are targeted.
Use of cutting-edge technology to ensure the most effective and safe light delivery.
Detailed instructions on post-treatment care, including avoiding sunlight for a specified period due to increased light sensitivity.
Management of any temporary side effects, such as redness or swelling in the treated area.

Other

Ongoing check-ups to track tumor response, cancer remission, or healing of treated lesions.
Emotional and psychological support throughout your treatment journey.
Information on diet, lifestyle, and self-care practices to optimize your recovery and maintain long-term health.
Access to support resources, including counseling and patient communities.

Extra add-ons

Airport transfer

Personal coordinator

HealthDocs translate

Language Assistance

Visa Support

AiroCare

AiroMedical support

Payment protection

Patient advocacy

Price match

Meet the provider

Dr. med. Gerhard Siebenhuner

holistic and regenerative medicine, biological cancer therapy and complementary oncology, anti-aging

9.30

Excellent

Gallery

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Location

Vilbeler Landstraße 45B, 60388 Frankfurt am Main, Germany

FAQ

What is Photodynamic Therapy (PDT)?

Photodynamic Therapy (PDT) is a treatment that uses light to activate photosensitizing agents, which are chemicals that make cancerous or abnormal cells sensitive to light. When these agents are exposed to specific wavelengths of light, they produce reactive oxygen molecules that destroy the target cells while minimizing damage to surrounding healthy tissue.

How does PDT work?

PDT involves three key steps: first, a photosensitizer (light-sensitive agent) is administered to the patient. Next, the photosensitizer accumulates in cancerous or abnormal cells. Finally, the area is exposed to a specific wavelength of light, which activates the photosensitizer and produces reactive oxygen species that damage and destroy the target cells.

Is PDT safe?

Yes, PDT is generally considered safe. It is a minimally invasive treatment with low risk of side effects. However, some patients may experience temporary redness, swelling, or mild discomfort at the treatment site. It’s important to follow post-treatment instructions, including avoiding direct sunlight, to prevent any potential issues.