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Department of nuclear medicine

Prof. Dr. med. Frank Grunwald
nuclear medicine

About the department

The department of nuclear medicine at University Hospital Frankfurt am Main of Goethe-University is one of the leading nuclear medicine facilities in Europe. In addition to excellent clinical care at the highest level, trend-setting participation in numerous innovative studies characterizes the clinic. An international team of experts guarantees reliable and optimized diagnostics and therapy, the expertise of which is a valuable source of second opinions. Numerous specializations in thyroid treatment and complex tumour diseases, among others, have grown out of the long-established tradition of nuclear medicine in Frankfurt. The department is a part of the University Center for Tumor Diseases (UCT) as a diagnostic and treatment facility.

In the field of isotope diagnostics, all standard nuclear medical procedures and special examinations are offered. The department offers 7 types of Positron emission tomography-computed tomography (PET/CT), scintigraphies of various organs, and isotope therapies with particular attention to the thyroid and prostate glands.

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Treatment and diagnostic focus of the department

Treatment priorities:

  • Hyperthyroidism and hypothyroidism
  • Autoimmune diseases of the thyroid, including Graves' disease, Hashimoto's disease
  • Thyroid Autonomy (Hot Nodes)
  • Nodular changes in the thyroid gland, enlarged thyroid gland, or thyroid cysts.
  • Thyroid cancer (thyroid carcinoma)
  • Inflammatory changes in the thyroid gland, including de Quervain's thyroiditis
  • Control after radioiodine therapy or thyroid surgery
  • Thyroid diagnostics during pregnancy
  • Prostate cancer

Diagnostic options:

  • Thyroid ultrasound
  • Thyroid scintigraphy
  • Fine-needle puncture
  • 131 I radioiodine test
  • Targeted prostate biopsy
  • Scintigraphy of different organs (visualization, functional testing with mild radiation) 

Positron emission tomography/Computed tomography PET/CT:

  • Fluoride-PET/CT (bone metabolism)
  • PSMA PET/CT (for prostate cancer)
  • FDG-PET/CT (brain metabolism)
  • Amyloid PET/CT (suspected of Alzheimer's disease)
  • DOPA PET/CT (for the detection of pheochromocytoma, paraganglioma, medullary thyroid carcinoma, insulinoma)
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Doctor profile


  • 1978 - 1984 Study of Human Medicine at the University of Bonn
  • 1984 Medical state examination
  • 1984 Admission to medical practice
  • 1984 - 1986 Research Fellowship at the Institute of Physiology I of the University of Bonn
  • 1986 Doctoral Degree
  • 1990 Board certification in Nuclear Medicine
  • 1992 Habilitation in Nuclear Medicine and appointment as PD
  • 1997 Appointed as an Extraordinary Professor


  • 1992 Senior Physician in the Department of Nuclear Medicine
  • 1994 Leading Senior Physician in the Department of Nuclear Medicine
  • 1999 Head of the Department of adult and pediatric nuclear medicine at University Hospital Frankfurt am Main of Goethe-University

Awards, memberships, publications

  • Co-editor of the standard German textbook in the field of nuclear medicine
  • Author of 500 publications
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