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Prof. Dr. med. Stefan Zeuzem image

Department of internal medicine (gastroenterology, hepatology, endocrinology, diabetology, nutritional medicine)

Prof. Dr. med. Stefan Zeuzem
internal medicine, gastroenterology, hepatology, endocrinology, diabetology, nutritional medicine

About the department

The department of internal medicine (gastroenterology, hepatology, endocrinology, diabetology, nutritional medicine) at University Hospital Frankfurt am Main of Goethe-University provides diagnosis and therapy of all diseases, including oncological problems in the specialist areas. The department has an efficient and excellently equipped central endoscopy facility in which all diagnostic and therapeutic endoscopic examinations of the bronchi, oesophagus, stomach, small and large intestine, bile ducts, and pancreas can be carried out. Special parts of the department include University Liver Center (founded in 2007) and University Lung Center, with interdisciplinary teams working together in a specified narrow area for best results. In 2018, another liver-focusing group formed - The Translational Hepatology Section, combining translational research with practical clinical application.

Using an endoscope, bleeding from the gastrointestinal tract and the bronchial system can be stopped, polyps can be removed, and a narrowing of the oesophagus, intestine, or bile ducts can be expanded endoscopically. Within the framework of interventional endoscopy, tumours can be treated in a targeted manner (laser treatment, insertion of metal and plastic prostheses, photodynamic therapy, etc.). All systemic chemotherapies are carried out following the guidelines.

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Treatment and diagnostic focus of the department

Bronchoscopy:

  • Transbronchial biopsy
  • Bronchoalveolar lavage

Oesophagus-Gastro-Duodenoscopy (EGD):

  • Video, chromo, and zoom endoscopy with biopsy
  • Treatment of oesophagal, gastric, and intestinal ulcers (injections, clips, fibrin glue)
  • Dilation and bridging of stenoses (bougienage, endoprostheses)
  • Mucosectomy for dysplasia or early carcinoma
  • Photodynamic Therapy
  • Polypectomy
  • Argon plasma coagulation treatment 
  • Endosonography with transmural puncture option
  • Percutaneous endoscopic gastrostomy (PEG), insertion of feeding tubes

Endoscopic retrograde cholangiopancreatography (ERCP):

  • Video endoscopy with biopsy and brush cytology
  • Endoscopic papillotomy of the biliary and pancreatic ducts
  • Stone extraction from the biliary and pancreatic ducts, mechanical lithotripsy
  • Endosonography with radial and linear scanners and transmural puncture
  • Dilation of benign and malignant duct stenoses
  • Insertion of plastic and metal stents in duct stenosis
  • Photodynamic Therapy
  • Extracorporeal shock wave lithotripsy

Percutaneous transhepatic choledochal drainage (PTCD):

  • Percutaneous insertion of pigtail catheters, Yamakawa prostheses, or metal stents
  • Photodynamic Therapy
  • Cholangioscopy

Contrast-enhanced sonography

Ultrasound-guided procedures:

  • Sonographically-assisted puncture
  • Sonographically controlled fine-needle puncture
  • Sonographically controlled drainage
  • Sonographically guided alcohol injection in hepatocellular carcinoma (PAI)
  • Sonographically guided radiofrequency ablation of hepatocellular carcinoma
  • elastographic examination of the liver and thyroid
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Doctor profile

Education

  • 1978-1985 Medical education at the University of Frankfurt a.M., Newcastle upon Tyne, UK, and Cambridge, UK 
  • 1986-1999 Medical specialization in Internal Medicine, Gastroenterology, Endocrinology, Intensive Care Medicine 
  • 1992 Habilitation, University of Frankfurt a.M. 
  • 1986 Doctoral-thesis, University of Frankfurt a.M. (summa cum laude) 
  • 1985 Approbation as Medical Doctor 1985 Final Medical Examination 

Experience

  • since 2007 Professor of Medicine (W3/C4), Head of the Department of internal medicine (gastroenterology, hepatology, endocrinology, diabetology, nutritional medicine) at University Hospital Frankfurt am Main of Goethe-University
  • 2002-2007 Professor of Medicine (C4), Director Department of Medicine II, Saarland University Hospital 
  • 1998-2002 Associate Professor, Department of Medicine, University Hospital Frankfurt 
  • 1993-2002 Junior Faculty, Department of Medicine, University Hospital Frankfurt 
  • 1993 Postdoctoral Researcher, Howard Hughes Medical Institute, Yale University Medical School, USA 
  • 1990-1991 DFG-research scholarship, Max-Planck-Institute for Biophysics, Frankfurt a.M. 
  • 1985-1986 Military Service, Giessen Military Hospital

Awards, memberships, publications

  • Member of the American Association for the Study of Liver Diseases (AASLD)
  • Member of the European Association for the Study of the Liver (EASL)  
  • Member of the German Society for Digestive and Metabolic Diseases (DGVS)  
  • Member of the German Society for Internal Medicine (DGIM)
  • 2019 President (elect) German Society for Digestive and Metabolic Diseases (DGVS) 
  • since 2016 Associate Editor of Gastroenterology 
  • 2010-2016 Board Member German Society for Digestive and Metabolic Diseases (DGVS) 
  • since 2010 Editorial Advisory Board Nature Reviews Gastroenterology and Hepatology 
  • 2010-2014 Associate Editor Journal of Hepatology 
  • 2007-2014 Speaker of the BMBF-Cluster “Host and viral determinants for susceptibility and resistance to hepatitis C virus infection” 
  • 2004-2013 Speaker of DFG-Clinical Research Group “Mechanisms of resistance development and optimization of antiviral strategies”
  • Author of more than 900 publications
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