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Prof. Dr. med. Frank Tacke image

Department of internal medicine (hepatology and gastroenterology)

Prof. Dr. med. Frank Tacke
internal medicine, gastroenterology, hepatology, diabetology

About the department

The department of internal medicine (hepatology and gastroenterology) at University Hospital Charite Berlin specialises in diagnosing and treating liver, bile ducts and gastrointestinal diseases. Experienced doctors in the department provide the latest and minimally invasive therapy methods. In addition, the department's specialists tightly cooperate with surgeons and radiologists to offer full-spectrum treatment for the patients. It is worth mentioning that the head physician of the department takes part in therapy guidelines development in the field of liver diseases and infections. Moreover, the chief doctor is a member of national and international societies. Furthermore, the department of internal medicine leads numerous research projects and clinical studies in partnerships with scientific organisations

The treatment focus of the department includes therapy for the liver, bile ducts and pancreas diseases. In addition, patients with chronic inflammatory bowel disease and pathologies of the stomachs get qualified medical help at the department. Doctors also treat nutritional disorders such as obesity and short bowel syndrome.

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Treatment and diagnostic focus of the department


  • ultrasound diagnostics
  • endoscopy
  • endosonography
  • ERCP (Endoscopic Retrograde Cholangiopancreatography)
  • H2 breath tests for bacterial overgrowth
  • C13 breath tests for Helicobacter pylori, gastric emptying disorders and pancreatic insufficiency
  • Oesophagal and anorectal manometry
  • pH-metry with impedanceometry
  • electrogastrography (private service)
  • pressure measurement of the anal sphincter
  • chromoendoscopy
  • capsule endoscopy 
  • magnetic resonance imaging of the intestine 
  • bone densitometry

Pancreatic diseases treatment:

  • acute and chronic inflammation
  • pancreatic tumours
  • narrowing or injuries of the pancreatic duct
  • pancreatic stones
  • cysts

Oesophagus and gastroesophageal occlusive apparatus:

  • gastroesophageal Reflux Disease
  • achalasia and nonspecific oesophagal motility disorders (e.g., nutcracker oesophagus)
  • ulcers
  • gastritis
  • stomach tumours
  • voiding disorders

Small intestine:

  • lactose intolerance/lactose malabsorption
  • fructose malabsorption
  • bacterial miscolonization

Large intestine and pelvic floor:

  • dysmotility
  • chronic inflammatory bowel disease
  • pelvic floor dyssynergia
  • incontinence

Liver surgeries:

  • minimally invasive liver surgery (keyhole technique) 
  • robot-assisted surgery
  • liver resections

Gastrointestinal oncology:

  • systemic chemotherapy
  • endoscopic therapy (e.g. stenting, laser therapy and bile duct drainage)
  • local ablative therapy methods
  • radiotherapy
  • symptomatic treatment such as pain management and nutritional therapy
  • endoscopic therapy of colorectal neoplasia
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Doctor profile


  • Study of human medicine, Hannover Medical School (MHH)
  • DAAD scholarship holder, MD Anderson Cancer Center, Houston, TX, USA
  • Doctorate PhD (MHH, Dept. Gastroenterology and Hepatology)
  • 2008 German board certification Internal Medicine
  • 2011 German board certification Gastroenterology          
  • 2012 German board certification Intensive Care Medicine
  • 2014 German board certification Infectious Diseases           
  • 2017 Fellow of the European Board of Transplant Medicine (UEMS)         
  • 2019 German board certification Endocrinology & Diabetology


  • 2004-2006 DFG fellow, Mount Sinai School of Medicine, New York, NY, USA
  • 2006-2019 Med. Clinic III, University Hospital Aachen (UKA), Senior Physician (most recently Head Senior Physician)
  • 2012-2019 W2 professor for hepato-gastroenterology at the RWTH Aachen University
  • since 2019 W3 professor of internal medicine with specialization in hepatology and gastroenterology; Director of the Medical Clinic Hepatology and Gastroenterology, Campus Virchow-Klinikum (CVK) and Campus Charité Mitte (CCM)

Awards, memberships, publications

  • American Association for the Study of the Liver (AASLD)
  • German Society for Infectious Diseases (DGI)
  • German Society for Internal Medicine (DGIM)
  • German Society for Internal Intensive Care and Emergency Medicine (DGIIN)
  • German Society for Digestive and Metabolic Diseases (DGVS)
  • German Liver Foundation (associated scientist)
  • European Academy for Tumor Immunology (EATI)
  • European Association for the Study of the Liver (EASL)
  • International Liver Transplant Society (ILTS)
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