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Prof. Dr. med. Alexander Muacevic image

Department of radiosurgery

Prof. Dr. med. Alexander Muacevic
radiation medicine, radiosurgery

About the department

The department of radiosurgery is recognized as International Reference Center for CyberKnife and ZAP-X technologies. Over 10,000 patients were treated at the centre. Including the years of implementation of the GammaKnife method, the precursor technology to CyberKnife, the department's physicians have almost 30 years of experience in the field of radiosurgery. In addition to the heading professor, the experts include the former head of the CyberKnife Center of the University Hospital Charite Berlin. The department is involved in scientific work, developing the science behind radiosurgical technology in cooperation with universities and medical societies. Many of the patients were treated in close consultation with colleagues of the University of Munich. The International Radiosurgery Society awarded the department for quality and highest standard medical services.

Radiosurgery is a method of precise radiation therapy used in cancer treatment. The main indications for radiosurgery are acoustic neuromas, meningiomas, and malignant melanomas of the eye (uveal melanoma). Treatment does not involve wounds or openings. It is painless and usually requires one session. The technologies are Cyberknife, GammaKnife and ZAP-X for brain cancer.

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Treatment and diagnostic focus of the department

Disorders treated with radiosurgery:

  • Acoustic neuroma
  • Meningioma
  • Angioma / AVM
  • Brain metastases
  • Trigeminal neuralgia
  • Uveal melanoma (eye cancer)
  • Prostate cancer (PSA < 15 ng/ml, Gleason 6 and 7)
  • Prostate cancer (metastases)
  • Spinal neurinoma
  • Spinal meningioma
  • Lung cancer (stage I/II)
  • Lung metastases
  • Primary liver carcinoma
  • Liver metastases
  • Lymph nodes
  • Singular lymph node metastasis
  • Renal cell carcinoma
  • Urothelial carcinoma

The treatment procedure:

  • Preparation (For lesions located in the brain, an individual headrest is moulded)
  • Imaging (CT and MRI)
  • Treatment planning (The CT and MRI data are logged onto a computer so that the attending physicians and specialized medical physicists can plan and simulate the number, intensity, and direction of the radiation beams)
  • Gentle treatment (Cyberknife and ZAP-X treatment)
  • End of treatment (usually, one treatment session is required)
  • Checkups (regular outpatient follow-up examinations)
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Doctor profile


  • 1989 – 1995 Medical studies at the Johannes Gutenberg University in Mainz
  • 1990 Fellowship from Boehringer Ingelheim KG, Department of Pharmacology, Ridgefield, Connecticut, USA (Dr. Wegner)
  • 1991 – 1995 Stays abroad in Los Angeles (USC), Charlottesville, Virginia and London (Institute of Neurology and Neurosurgery)
  • 1995 Ph.D. with Prof. Dr. A. Perneczky, Mainz
  • 1996 – 2003 Doctor in internship, assistant doctor and then specialist in neurosurgery, neurosurgical clinic, Klinikum Großhadern, Ludwig-Maximilians-University Munich
  • 2005 Completed further training as a radiosurgery
  • 2006 Habilitation at the Ludwig-Maximilians-University Munich
  • 2013 appointment as professor at the Ludwig-Maximilians-University Munich


  • 2005 - founder and the head of European Radiosurgery Centre Munich

Awards, memberships, publications

  • 2003 Aesculap Prize of the European Society of Neurosurgery
  • since 2007 Member of the Supervisory Board of the International Radiosurgical Society (The Radiosurgery Society)
  • 2011 – 2013 President of the International Society of Radiosurgery (The Radiosurgery Society)
  • 2014 – 2015 Chairman of the Board of Directors of The Radiosurgery Society
  • Member of the: ASTRO (American Society of Radiation Oncology), ISRS (International Stereotactic Radiosurgery Society), DEGRO (German Society for Radiation Oncology), Working Group on Stereotaxy, EANS (European Association for Neurosurgery)
  • Author of over 100 specialist publications, numerous lectures at international and national scientific congresses, the foundation of the innovative publication platform in 2012 with Dr. John R. Adler, Stanford School of Medicine, USA
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