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Prof. Dr. Semra Kahraman image

Department of in vitro fertilization (IVF) andrology with genetics centre

Prof. Dr. Semra Kahraman
reproductive medicine

About the department

The department of in vitro fertilization (IVF) andrology with genetics centre at Memorial Sisli Hospital Istanbul offers a full range of first-class medical services for patients with fertility problems. The main specialization of the department is in vitro fertilization, which helps women achieve the desired pregnancy. Doctors of the department are engaged in clinical research activities and introduce innovative approaches to treating infertility, thanks to which they achieve excellent results. The department was the first in Turkey to apply methods such as surgical sperm extraction and microinjection, embryo freezing procedures, endometrial cell culture and preimplantation genetic diagnosis. More than 10,000 babies were born within the hospital walls thanks to professional infertility treatment.

The department consists of the Center for In Vitro Fertilization, the Center for Andrology and the Perinatal Center, and various specialized laboratories. The department is the only one in Turkey that unites all related disciplines under one roof. In addition, the department is the first and only centre certified by the Ministry of Health for training doctors, embryologists, biologists and nurses in vitro fertilization (IVF) procedures. In addition to diagnosing and treating infertility diseases, the medical team performs preimplantation genetic diagnosis of embryos in couples at risk of congenital pathologies. This diagnosis allows doctors to identify thalassemia, spinal muscular atrophy, haemophilia and other pathologies in the embryo.

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Treatment and diagnostic focus of the department


  • Polycystic ovary syndrome (PCOS)
  • Theroid problems 
  • Premature ovarian failure 
  • Cervical mucus problems 
  • Uterine fibroids 
  • Fallopian tube damage or blockage
  • Endometriosis 
  • Pelvic inflammatory disease 
  • Sterilisation 
  • Low sperm count 
  • Testicular surgery 
  • Ejaculation disorders 
  • Hypogonadism


  • Anamnesis 
  • Physical examination 
  • Laboratory and biochemical tests
  • Hormone panel
  • Speculum examination 
  • Pap smear test (to detect potentially precancerous and cancerous processes in the cervix)
  • Ultrasound examination
  • Computed tomography (CT scan) 
  • Magnetic resonance imaging (MRI) 
  • Semen analysis (evaluates sperm count, motility and morphology)
  • FISH semen analysis
  • Testicular sperm aspiration
  • Preimplantation genetic diagnosis
  • HLA typing (to identify immune system variations)
  • Analysis of the structure and number of chromosomes
  • Cytogenetic study


  • Ovulation induction
  • Intrauterine insemination
  • In vitro fertilization
  • Therapeutic hysteroscopy
  • Therapeutic laparoscopy
  • Cryopreservation of sperm by microdissection of the testis
  • Immunoglobulin therapy
  • Oocyte maturation in the laboratory
  • Other treatment options 
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Doctor profile


  • 2004 Professorship, Faculty of Medicine, Yeditepe University, Istanbul, Turkey
  • 1994 Assistant Professorship, Faculty of Medicine, Ankara University, Ankara, Turkey
  • 1983 - 1989 Professional training in Gynecology and Obstetrics, Faculty of Medicine, Ankara University, Ankara, Turkey
  • 1973 - 1981 Study of Human Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey


  • Since 2000 Head of the Department of Reproductive Medicine at the Memorial Sisli Hospital Istanbul.
  • 1996 - 1997 Work at the Institute of Reproductive Genetics, Chicago, USA
  • 1996 - 1997 Work at the Weill Cornell's Center for Reproductive Medicine, New York, USA
  • 1996 - 1997 Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Vilvoorde, Belgium
  • 1993 - 2000 Head of the Center for Reproductive Medicine, Sevgi Hospital, Ankara, Turkey
  • 1991 - 1992 Work at the Fertility Center, Oslo University Hospital, Norway

Awards, memberships, publications

  • 2018 and 2017 American Society for Reproductive Medicine (ASRM) Star Awards
  • 2015 Medical Travel Journal Awards – Department of Reproductive Medicine at the Memorial Sisli Hospital Istanbul is recognized as the International Hospital of the Year in the field of its specialization, London, UK
  • 2014 Grant for Innovations in Fertility Treatment, Project "Detection of markers of oocyte competence using maturation analysis" – one of the best projects in the field of fertility research, Munich, Germany
  • 2013 Award for Scientific Contribution in Reproductive Medicine, Ankara, Turkey
  • 2008 Lifetime Achievement Award, Turkish Society for Reproductive Medicine (TSRM)
  • 2004 Award for the Best Researcher of the Year (Human Embryonic Stem Cell Research), TEMPO Journal
  • 2001 Best Presentation Award
  • 1997 and 1996 TUBİTAK Honorable Award
  • 1996 Poster Award
  • President of the Preimplantation Genetic Diagnosis International Society (PGDIS)
  • Board Member of the Preimplantation Genetic Diagnosis International Society (PGDIS)
  • Member of the European Society of Human Reproduction and Embryology (ESHRE)
  • Member of the American Society for Reproductive Medicine (ASRM)
  • Jury Member on Awarding of the Royan Institute
  • Member of the Turkish Society for Reproductive Medicine (TSRM)
  • Member of the Turkish Society of Obstetrics and Gynecology (TJOD)
  • Association for Reproductive Medicine (ÜTD)
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