Oropharyngeal cancer treatment
Oropharyngeal cancer is a malignant tumour that develops from the epithelium of the oropharynx, primarily due to excessive alcohol consumption or smoking. Initial symptoms are discomfort when swallowing, pain and sensation of a foreign body in the throat. In the treatment, oncologists use surgery, local and systemic chemotherapy, immuno- and targeted therapy, radiotherapy and proton beams.
Oropharyngeal cancer is a tumour in the part of the pharynx near the mouth. A whole group can be diagnosed in this place:
- Tonsil cancer (50%) originates from the mucous membrane of the tonsils. A malignant neoplasm develops in the lymphoid tissue of the oropharynx, grows without a clear boundary, and often appears to be an infiltrate or ulcer.
- Tumours of the root of the tongue develop from the most deeply located part of the organ, which lies closer to the pharynx (24.5%).
- Tonsillar pillar cancer grows from lymphatic and adenoid tissues, part of tonsillar formations.
- Vallecula cancer is a formation in the depressions between the edge of the epiglottis and the root of the tongue.
- Epiglottis cancer occurs in the part of the larynx, which is located above the vocal cords, which performs a delimiting function, preventing food from entering the respiratory tract.
Cancer of the oropharynx is considered aggressive because it quickly invades the lymph nodes. The most severe risk factor is alcohol abuse. 75% of patients had a history of drinking large amounts of alcohol during their lifetime. Smoking also stimulates tissue damage. Among people who do not have these habits, the human papillomavirus or chronic inflammatory diseases (pharyngitis, tonsillitis) can provoke a malignant process.
The disease accounts for 12% of all head and neck tumours. The ratio of sick men to women is five to one because of the lower prevalence of alcoholism among women. Most tumours are detected in people after 35.
It's important to note that 50% of patients already have metastases in the lymph nodes when the tumour is detected. So patients should be warned by the appearance of lumps on the neck, sore throat and difficulty swallowing.
Oropharyngeal malignancy is sensitive to chemoradiotherapy. Therefore, chemotherapy is usually used first and then radiation therapy, but recently methods are often combined - during radiation therapy, chemo drugs are administered intravenously about once every three weeks. In advanced cases, doctors frequently prescribe immunotherapy, local chemotherapy, targeted medications and proton therapy.
Where can I get Oropharyngeal cancer treatment?
What are the best clinics for Oropharyngeal cancer treatment?
Who are the best doctors for Oropharyngeal cancer?
Prof. Dr. med. Christian Brandts from University Hospital Frankfurt am Main of Goethe-University
Prof. Dr. med. Timo Stover from University Hospital Frankfurt am Main of Goethe-University
Prof. Dr. med. Hubert Serve from University Hospital Frankfurt am Main of Goethe-University
Prof. Dr. Jordi Coromina from Teknon Medical Centre Barcelona
Prof. Dr. Joan Carles Galceran, Ph.D. from Teknon Medical Centre Barcelona