Basal ganglia disease treatment

We found 28 clinics & 27 doctors for Basal ganglia disease Worldwide. AiroMedical ranks among 444 hospitals based on qualification, experience, success rate, and awards.

The basal ganglia receive information from the cerebral cortex (above) and the brainstem (below) and form a connected chain. Their main functions are related to the initiation and integration of movement. In the case of disturbances in the basal ganglia, the corresponding areas of the cortex begin to discharge uncontrollably, leading to the development of different diseases.

Basal ganglia (nuclei) in anatomy are usually called a complex of accumulations of grey matter in the brain's white matter. They have close connections with other structures of the brain and perform the following functions:

  • Regulate motor processes;
  • Responsible for the normal functioning of the autonomic nervous system;
  • Carry out the integration of nervous activities.

Thus, a change in the anatomy and functioning of these structures is usually associated with the appearance of pathologies. The primary diseases related to basal ganglia damage are Parkinson's, Huntington's, cerebral palsy, and PAP syndrome.

Several diseases have now been identified that are etiologically related to the state of the basal ganglia. Most of them are severe and degenerative pathologies:

  • Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz disease) is a rare autosomal recessive disorder that predominantly affects the basal ganglia and is associated with iron accumulation in the brain.
  • Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) is a rare brain disorder that causes balance, movement, eye coordination, and thinking problems.
  • Multiple system atrophy (Shy-Drager syndrome) is accompanied by signs of autonomic imbalance (orthostatic hypotension, urinary problems and erectile dysfunction), Parkinson's symptoms (decreased mobility and tremor of the limbs), and cerebellar ataxia.

Calcification of basal ganglia, pigmentary pallidal degeneration, and neurogenic orthostatic hypotension are also caused by certain disorders of the basal ganglia of the brain.

In the case of damage to the basal ganglia, there is a violation of the flexibility of behaviour: a person can hardly adapt to the difficulties encountered when performing the standard algorithm. Furthermore, adjusting to the performance of more logical actions in these conditions is difficult. In addition, the ability to learn, which is slow, decreases, and the results remain minimal for a long time. Patients often encounter movement disorders: all activities become intermittent, as if twitching, tremors (tremors of the limbs) or involuntary actions (hyperkinesis) occur.

Diagnosis of damage to the basal ganglia is based on clinical manifestations of the disease and modern neurological imaging methods such as CT and MRI scans of the brain. Basal ganglia disease treatment depends on its cause and is carried out by a neurologist. As a rule, lifelong administration of antiparkinsonian drugs is required. The ganglion does not recover, but drug treatment and rehabilitation significantly relieve symptoms and improve the quality of the patient's life. Some doctors recommend stem cell therapy as an additional option for basal ganglia damage to bust tissue regeneration.

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6 countries and 17 cities for Basal ganglia disease